Pyrrolidine → HCID 13912882, compound

Participants

Reaction Steps

To a solution of 4.24 g of 5-amino-2-methoxy-4-nitrobenzoic acid in 30 ml of N,N-dimethylformamide was added 3.24 g of N,N'-carbonyldiimidazole at room temperature. After 30 minutes, 5 ml of pyrrolidine was added, and the mixture was stirred for 2 hours. The solvent was evaporated under reduced pressure, and the residue was recrystallized from ethyl acetate to give the title compound, m.p. 159°-162° C., yield of 4.16 g.

Provenance & Evidence