79893-21-3 → HCID 13912878, compound

HRID 1789077Notes

Reaction equation

HRID 1789077 reaction equation
[NH2:1][C:2]1[C:3]([N+:14]([O-:16])=[O:15])=[CH:4][C:5]([O:12][CH3:13])=[C:6]([CH:11]=1)[C:7](OC)=[O:8].O.[NH3:18]>O1CCOCC1>[NH2:1][C:2]1[C:3]([N+:14]([O-:16])=[O:15])=[CH:4][C:5]([O:12][CH3:13])=[C:6]([CH:11]=1)[C:7]([NH2:18])=[O:8]

Participants

4

Reactant 2

HCID 1288398779893-21-3HCID 12896473Azane;hydrate

Product 1

HCID 13912878HCID 13912878, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

To a solution of 5.66 g of methyl 5-amino-2-methoxy-4-nitrobenzoate in 200 ml of dioxane was added 50 ml of 28 % ammonia water, and then the mixture was allowed to stand at room temperature for 40 hours. The solvent was evaporated under reduced pressure, and the residue was recrystallized from dioxane to give the title compound, m.p. 250°-257° C., yield of 4.30 g.

Workup

  1. customThe solvent was evaporated under reduced pressure
  2. customthe residue was recrystallized from dioxane

Sources & evidence

ORD record
ord-f895edc41e134a04912976c873e74c91
Source dataset
uspto-grants-1987_08
Patent number
US04686292

Reaction notes

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