反应详情

A suspension of 3.62 g of N,N-dimethyl 5-amino-2-methoxy4-nitrobenzamide and 150 mg of 10 % palladium carbon in 140 ml of ethanol was stirred at 70°-80° C. under a hydrogen atmosphere. After the absorption of hydrogen was completed, the catalyst was removed by filtration, and the filtrate was evaporated to dryness to give crude N,N-dimethyl 4,5-diamino2-methoxybenzamide, which was then dissolved in 30 ml of tetrahydrofuran.

1. customAfter the absorption of hydrogen
2. customthe catalyst was removed by filtration
3. customthe filtrate was evaporated to dryness