Hydrochloric Acid → HCID 11268957, compound

Participants

Reaction Steps

A mixture of 2-imino-5-{4-[2-(5-methyl-2-pyridyl)ethoxy]benzyl}-4-thiazolidinone (8.0 g), 2N HCl (80 ml) and ethanol (80 ml) was refluxed for 16 hours. The reaction solution was neutralized with a saturated aqueous solution of sodium hydrogencarbonate to yield crystals. The crystals were collected by filtration and recrystallized from ethanol to give 5-{4-[2-(5-methyl-2pyridyl)ethoxy]benzyl}-2,4-thiazolidinedione as colorless prisms (7.0 g, 87.5%), m.p. 192°-193° C.

Provenance & Evidence