Benzyl piperazine-1-carboxylate → HCID 131715233, compound

HRID 1789186Notes

Reaction equation

HRID 1789186 reaction equation
[C:1](N1CCNCC1)([O:3][CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:2].C(N[CH:20]1[CH2:24][CH2:23][NH:22][CH2:21]1)=O>>[C:1]([C:23]1[NH:22][O:3][C:4]2[CH:5]=[CH:6][CH:7]=[CH:21][C:20]=2[CH:24]=1)([O:3][CH2:4][C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1)=[O:2]

Participants

3

Reactant 2

HCID 643495Benzyl piperazine-1-carboxylateHCID 15594625HCID 15594625, compound

Product 1

HCID 131715233HCID 131715233, compound

Procedure

In the described fashion as Example 2(b)-2(e), replacing the N-carbobenzoxypiperazine in Example 2(e) with 3-formamidopyrrolidine, one can obtain compound (F) (R8 =CH3, R9 =C2H5, R10 =C6H5, ##STR20##

Sources & evidence

ORD record
ord-526999a3986c46a78f6d44b277824e83
Source dataset
uspto-grants-1987_08
Patent number
US04687770

Reaction notes

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