HCID 13982918, compound → HCID 13958392, compound

Participants

Reaction Steps

To a stirred solution of 4.0 g (0.0117 mole) of 1-(2,3-diacetoxypropyl)-1H-imidazo[4,5-c]quinolin-5-oxide (from Example 121, Part A) in 50 ml of methanol was added about 12 drops of 25% sodium methoxide solution. After one hour the product was collected by filtration, washed with methanol and recrystallized from ethanol to provide 1-(2,3-dihydroxypropyl)-1H-imidazo[4,5-c]quinolin-5-oxide, m.p. 240°-242° C. Analysis: Calculated for C13H13N3O3 : % C, 60.2; % H, 5.1; % N, 16.2; Found: % C, 60.0; % H, 5.0; % N, 15.8.

Provenance & Evidence