2-Propanol, 1-amino-2-methyl- → 2-Methyl-1-((3-nitroquinolin-4-yl)amino)propan-2-ol

HRID 1789439Notes

Reaction equation

HRID 1789439 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13].[OH:15][C:16]([CH3:20])([CH3:19])[CH2:17][NH2:18]>>[OH:15][C:16]([CH3:20])([CH3:19])[CH2:17][NH:18][C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[CH:9][CH:10]=2)[N:5]=[CH:4][C:3]=1[N+:12]([O-:14])=[O:13]

Participants

3

Reactant 2

HCID 951022-Propanol, 1-amino-2-methyl-HCID 112758084-Chloro-3-nitroquinoline

Product 1

HCID 139583422-Methyl-1-((3-nitroquinolin-4-yl)amino)propan-2-ol

Procedure

Using the method of Example 1, 4-chloro-3-nitroquinoline was reacted with 2-hydroxy-2-methylpropylamine to provide 4-(2-hydroxy-2-methylpropylamino)3-nitroquinoline, m.p. 234°-244° C. (dec.).

Sources & evidence

ORD record
ord-79e71bee98e74baf9f6c9abcace69231
Source dataset
uspto-grants-1987_08
Patent number
US04689338

Reaction notes

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