Veratraldehyde → HCID 13982912, compound

HRID 1789444Notes

Reaction equation

HRID 1789444 reaction equation
[NH2:1][C:2]1[CH:3]=[N:4][C:5]2[C:10]([C:11]=1[NH:12][CH2:13][CH:14]([CH3:16])[CH3:15])=[CH:9][CH:8]=[CH:7][CH:6]=2.[CH:17](=O)[C:18]1[CH:27]=[CH:26][C:23]([O:24][CH3:25])=[C:20]([O:21][CH3:22])[CH:19]=1>>[CH3:22][O:21][C:20]1[CH:19]=[C:18]([C:17]2[N:12]([CH2:13][CH:14]([CH3:16])[CH3:15])[C:11]3[C:10]4[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=4[N:4]=[CH:3][C:2]=3[N:1]=2)[CH:27]=[CH:26][C:23]=1[O:24][CH3:25]

Participants

3

Reactant 2

HCID 8419VeratraldehydeHCID 11298872N4-(2-methylpropyl)quinoline-3,4-diamine

Product 1

HCID 13982912HCID 13982912, compound

Procedure

Following the general method of Example 195, Step B, 3-amino-4-(isobutylamino)quinoline was reacted with veratraldehyde to provide 2-(3,4-dimethoxyphenyl)-1-isobutyl-1H-imidazo[4,5-c]quinoline, melting point 192°-199° C. Analysis: Calculated for C20H23N3O2 : % C, 73.1; % H, 6.4; % N, 11.6. Found: % C, 72.7; % H, 6.3; % N, 11.4.

Sources & evidence

ORD record
ord-34c8435756eb44168d336df0c543e20d
Source dataset
uspto-grants-1987_08
Patent number
US04689338

Reaction notes

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