HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylimidazole → 3-Methyl-1-[2-[4-((methylsulfonyl)amino)phenyl]-2-oxoethyl]-1H-imidazolium chloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylimidazole | HCID 1390 | — |
| Reactant | Methanesulfonamide, N-[4-(2-chloroacetyl)phenyl]- | HCID 116629 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | 3-Methyl-1-[2-[4-((methylsulfonyl)amino)phenyl]-2-oxoethyl]-1H-imidazolium chloride | HCID 86741031 | — |
Reaction Steps
Heat a mixture of 160 g (0.646 mole) of N-[4-(2-chloro-1-oxoethyl)phenyl]methanesulfonamide, 55.7 g (0.678 mole) of 1-methyl-1H-imidazole and 2.1 L of acetonitrile at reflux for about 16 hours. Cool the mixture to room temperature and collect the solid and wash with 2 L of acetonitrile. Drying provides the title compound, which may be recrystallized from aqueous ethanol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04689341 |
| Source dataset | uspto-grants-1987_08 |
| ORD ID | ord-d7be8a0b10e1453c9251730ccc298a72 |
| Source note | uspto-grants-1987_08 |