HuagongsheHuagongshe Chemistry Print Report · For research reference only
Imidazole → HCID 20188399, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Imidazole | HCID 795 | — |
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | 4-Chloro-1-butanol | HCID 13569 | — |
| Reactant | tert-Butyldimethylsilyl chloride | HCID 28928 | — |
| Product | HCID 20188399 | HCID 20188399 | — |
Reaction Steps
The procedure followed is the same as that described in Example 7 substituting 4-chlorobutanol (326 g, 3.00 moles), tert-butyldimethylsilyl chloride (500 g, 3.31 moles), imidazole (225 g, 3.30 moles), and dimethylformamide (1600 ml). The crude product is fractionally distilled under reduced vacuum leaving a clear, colorless oil (475 g, 2.13 moles), BP α°C/0.3 mm.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04689345 |
| Source dataset | uspto-grants-1987_08 |
| ORD ID | ord-5212f1ae92a448f185b8372f231a0c2d |
| Source note | uspto-grants-1987_08 |