Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | HCID 13851850 | HCID 13851850 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | Cytidine | HCID 6175 | — |
Reaction Steps
In methanol (50 ml) is dissolved 2',3',5'-tri-O-acetyl-N4 -benzoylcytidine (0.53 g) followed by addition of concentrated NH4OH (5 ml) with stirring at 70° C. The mixture is stirred at 70° C. for 2.5 hours, at the end of which time ethanol is added. The mixture is allowed to stand at room temperature overnight to give colorless needles of cytidine. Yield 0.26 g (95.6%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04689404 |
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| Source dataset | uspto-grants-1987_08 |
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| ORD ID | ord-2131771375784b5dbff2e1c2b9f89ab5 |
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| Source note | uspto-grants-1987_08 |
|---|
