3-Aminopyrrolidine → HCID 9840664, compound

Participants

Reaction Steps

The title compound was prepared according to the procedure described in Example 4, Step 2, starting from 2-chloro-3-[2-(2-chlorophenoxy)ethoxy]pyrazine*(150 mg, 0.53 mmol) and 3-aminopyrrolidine (252 mg, 2.92 mmol) with the exception that a final extraction step between EtOAc and 5% aqueous NaOH was carried out. This gave 100 mg(56%) of the title product. Anal. (C16H19CIN4O2) C, H; N: calcd, 16.73; found, 16.0.

Provenance & Evidence