Piperazine → 3-(1-Piperazinyl)-2,6,7-trichloroquinoxaline

Participants

Reaction Steps

Piperazine (0.69 g, 8.06 mmol) was added to a stirred suspension of 2,3,6,7-tetrachloroquinoxaline (1.08 g, 4.03 mmol) in EtOH (125 mL) at room temperature. The mixture was stirred at room temperature for 8 h and filtered to give the product as a pale yellow solid: yield 0.88 g (69%), mp>300° C. MS m/z 316/318 (M)+.

Provenance & Evidence