Trifluoroacetic acid → HCID 53649209, compound

Participants

Reaction Steps

TFA (2 mL) was added to a solution of 4-(3-acetylsulfanyl-2-ethoxycarbonyl-1-methyl-propyl)-piperidine-1-carboxylic acid tert-butyl ester (0.17 g, 0.439 mmol) in methylene chloride (10 mL). The reaction was stirred for 90 min and concentrated under reduced pressure. The crude product was purified using HPLC (10→50% acetonitrile in water, 0.1% TFA) to give 2-acetylsulfanylmethyl-3-piperidin4-yl-butyric acid ethyl ester (101 mg, 54%) as the TFA salt.

Provenance & Evidence