Benzyl iodide → HCID 21302495, compound

Participants

Role	Name	HCID	Charge
Reactant	Benzyl iodide	HCID 12098	—
Reactant	ethyl (10R,15S)-3-oxo-1,4,12-triazatetracyclo[7.6.1.05,16.010,15]hexadeca-5,7,9(16)-triene-12-carboxylate	HCID 20578971	—
Product	HCID 21302495	HCID 21302495	—

Reaction Steps

Utilizing the material from Example 255 Step A, the title compound was prepared in analogous fashion using benzyl iodide as the alkyl halide and following the procedure of Step B–D of Example 255, as a viscous liquid. 1H NMR(CDCl3, 300 MHz) δ 1.60–2.0 (m, 2H), 2.55–2.95(m, 4H), 2.95–3.15 (m, 2H), 3.20–3.45 (m, 3H), 4.40 (q, J=16.1 Hz, 2H), 6.41 (d, J=7.1 Hz, 1H), 6.51 (d, J=7.1 Hz, 1H), 6.62 (t, J=7.1 Hz, 1H), 7.20–7.40 (m, 5H) ppm. MS (CI): 306 (M+H+).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07071186B2
Source dataset	uspto-grants-2006_07
ORD ID	ord-613b4223845d4184ab9b9410adf77fb2
Source note	uspto-grants-2006_07