3-(2-Naphthylthio)propionic acid → HCID 11374196, compound

Participants

Role	Name	HCID	Charge
Reactant	3-(2-Naphthylthio)propionic acid	HCID 517992	—
Reactant	1-(2-Pyrrolidin-1-YL-ethyl)-1H-indazol-6-ylamine	HCID 11276288	—
Product	HCID 11374196	HCID 11374196	—

Reaction Steps

According to the procedure for Example 49, 1-(2-pyrrolidin-1-yl-ethyl)-1H-indazol-6-ylamine and 3-(naphthalen-2-ylsulfanyl)-propionic acid were processed to provide the title compound. 1H NMR (500 MHz, DMSO-d6) δ ppm 1.84 (m, 2 H), 1.99 (m, 2 H), 2.79 (t, J=7.02 Hz, 2 H), 3.04 (m, 2 H), 3.40 (t, J=7.02 Hz, 2 H), 3.53 (m, 2 H), 3.71 (q, J=6.10 Hz, 2 H), 4.68 (t, J=6.26 Hz, 2 H), 7.06 (m, 1 H), 7.50 (m, 3 H), 7.70 (m, 1 H), 7.88 (m, 4 H), 8.09 (s, 1 H), 8.30 (s, 1 H), 9.62 (br s, N H); MS (DCI/NH3) m/z 445 (M+H)+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07071182B2
Source dataset	uspto-grants-2006_07
ORD ID	ord-23b09b32b2a14703a9e52e43225fe9da
Source note	uspto-grants-2006_07