HCID 22037252, compound → HCID 59038077, compound

HRID 1790374Notes

Reaction equation

HRID 1790374 reaction equation
[NH:1]1[CH2:5][CH2:4][CH2:3][C@@H:2]1[C:6]1[NH:10][N:9]=[C:8]([C:11]2[CH:16]=[CH:15][C:14]([F:17])=[CH:13][CH:12]=2)[C:7]=1[C:18]1[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=1.Cl.N1CCC(C2NN=C(C3C=CC(Cl)=CC=3)C=2C2C=CN=CC=2)C[CH2:26]1>>[CH3:26][N:1]1[CH2:5][CH2:4][CH2:3][C@@H:2]1[C:6]1[NH:10][N:9]=[C:8]([C:11]2[CH:12]=[CH:13][C:14]([F:17])=[CH:15][CH:16]=2)[C:7]=1[C:18]1[CH:23]=[CH:22][N:21]=[CH:20][CH:19]=1

Participants

3

Reactant 2

HCID 22037252HCID 22037252, compoundHCID 59038029HCID 59038029, compound

Product 1

HCID 59038077HCID 59038077, compound

Procedure

By following the method of Example C-75 and substituting (R)-5-(2-pyrolidinyl)-4-(4-pyridyl)-3-(4-fluorophenyl)pyrazole Example C-125) for 5-(4-piperidyl)-4-(4-pyridyl)-3-(4-chlorophenyl)pyrazole hydrochloride (Example C-74) the title compound was prepared: MS (M+H): 323 (base peak).

Sources & evidence

ORD record
ord-68e71c52b3254c508c88af67df123562
Source dataset
uspto-grants-2006_07
Patent number
US07071198B1

Reaction notes

Loading…