HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloroacetyl chloride → 1-[1-(4-Chloroacetamidomethylphenethyl)piperidin-4-yl]indoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloroacetyl chloride | HCID 6577 | — |
| Reactant | 1-[1-(4-Aminomethylphenethyl)piperidin-4-yl]indoline | HCID 22038221 | — |
| Product | 1-[1-(4-Chloroacetamidomethylphenethyl)piperidin-4-yl]indoline | HCID 22038374 | 62.1% |
Reaction Steps
1-[1-(4-Aminomethylphenethyl)piperidin-4-yl]indoline (0.1 g) and chloroacetyl chloride (0.026 ml) were treated as in Example 36 to give the title compound (0.074 g) as a pale yellow oil (yield: 62.1%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07071201B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-c405968da8c749ae9db01908a1174187 |
| Source note | uspto-grants-2006_07 |