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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1790414Generated: November 4, 2026

4-(2-Bromoethyl)benzenesulfonamide → 1-[1-(4-Sulfamoylphenethyl)piperidin-4-yl]indoline

https://huagongshe.com/reaction/1790414

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Bromoethyl)benzenesulfonamideHCID 14485091—
Reactant1-Piperidin-4-yl-2,3-dihydro-1H-indoleHCID 22028603—
Product1-[1-(4-Sulfamoylphenethyl)piperidin-4-yl]indolineHCID 2203831510.5%

Reaction Steps

1-(Piperidin-4-yl)indoline (300 mg) and 4-sulfamoylphenethyl bromide (400 mg) were treated as in Example 2 to give the title compound (60 mg) as a pale yellow powder (yield: 10%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07071201B2
Source datasetuspto-grants-2006_07
ORD IDord-58b15d9f5d06430c8c06f339cd5d714b
Source noteuspto-grants-2006_07