反应详情

1-(4-Piperidyl)indoline (0.1 g) was dissolved in ethanol (5 ml). After adding 4-vinylpyridine (0.16 ml), the resultant mixture was heated under reflux in a nitrogen atmosphere for 12 hr. Then the reaction solution was concentrated under reduced pressure and purified by silica gel column chromatography (toluene/acetone system) to give the title compound (0.064 g) as a colorless oil (yield: 42.5%).

1. temperatureunder reflux in a nitrogen atmosphere for 12 hr
2. concentrationThen the reaction solution was concentrated under reduced pressure
3. custompurified by silica gel column chromatography (toluene/acetone system)