HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-methyl-2-(tributylstannyl)-1H-pyrrole → 1-[1-(4-Fluorophenethyl)-piperidin-4-yl]-6-(1-methylpyrrol-2-yl)indoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-methyl-2-(tributylstannyl)-1H-pyrrole | HCID 2769397 | — |
| Reactant | 1-[1-(4-Fluorophenethyl)piperidin-4-yl]-6-bromoindoline | HCID 22037889 | — |
| Product | 1-[1-(4-Fluorophenethyl)-piperidin-4-yl]-6-(1-methylpyrrol-2-yl)indoline | HCID 22037910 | 16% |
Reaction Steps
1-[1-(4-Fluorophenethyl)piperidin-4-yl]-6-bromoindoline (0.1 g) and 1-methyl-2-tributylstannylpyrrole (0.37 g) synthesized in accordance with the method described in Tetrahedron Lett., 4407 (1986). were treated as in Production Example 13-2 to give the title compound (0.016 g) as a yellow oil (yield: 15.8%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07071201B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-dc576177fc81464e9394638c7b608ad8 |
| Source note | uspto-grants-2006_07 |