Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6-(Dimethylamino)pyridine-3-carbaldehyde → 5-bromo-N,N-dimethylpyridin-2-amine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6-(Dimethylamino)pyridine-3-carbaldehyde | HCID 11240577 | — |
| 반응물 | 1-[1-(4-Fluorophenethyl)piperidin-4-yl]-6-bromoindoline | HCID 22037889 | — |
| 생성물 | 5-bromo-N,N-dimethylpyridin-2-amine | HCID 3803041 | 150.9% |
반응 단계
1-[1-(4-Fluorophenethyl)piperidin-4-yl]-6-bromoindoline (0.5 g) and 2-dimethylamino-5-formylpyridine (0.345 g) were treated as in Example 130 to give the title compound (0.376 g) as a colorless oil (yield: 65.3%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07071201B2 |
| 출처 데이터셋 | uspto-grants-2006_07 |
| ORD ID | ord-49f9de68a7b64bc7bd7b5b8f35d39ebd |
| 출처 메모 | uspto-grants-2006_07 |