1-[1-(4-Fluorophenethyl)piperidin-4-yl]-6-bromoindoline → 1-[1-(4-Fluorophenethyl)piperidin-4-yl]-6-bromoindole

Participants

Reaction Steps

1-[1-(4-Fluorophenethyl)piperidin-4-yl]-6-bromoindoline (0.1 g) was dissolved in chloroform (27 ml). After adding manganese dioxide (2.75 g), the resultant mixture was heated under reflux for 4 hr. Then manganese dioxide was filtered off and the filtrate was concentrated under reduced pressure to give the title compound (0.480 g) as a yellow oil (yield: 96.5%).

Provenance & Evidence