HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Difluorophenethyl bromide → 1-[1-(2,4-Difluorophenethyl)-piperdin-4-yl]-6-bromoindoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Difluorophenethyl bromide | HCID 11298989 | — |
| Reactant | 1-(Piperidin-4-yl)-6-bromoindoline | HCID 22038170 | — |
| Product | 1-[1-(2,4-Difluorophenethyl)-piperdin-4-yl]-6-bromoindoline | HCID 22038309 | 60.1% |
Reaction Steps
1-(Piperidin-4-yl)-6-bromoindoline (3.0 g) and 2,4-difluorophenethyl bromide (3.1 g) were treated as in Example 2 to give the title compound (2.7 g) as a white powder (yield: 60%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07071201B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-232ee03a698e48479f56307e26524ce8 |
| Source note | uspto-grants-2006_07 |