HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-(3-Bromopropoxy)-4-fluorobenzene → 1-[1-(4-Fluorophenoxypropyl)-piperdin-4-yl]-6-bromoindoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-(3-Bromopropoxy)-4-fluorobenzene | HCID 260004 | — |
| Reactant | 1-(Piperidin-4-yl)-6-bromoindoline | HCID 22038170 | — |
| Product | 1-[1-(4-Fluorophenoxypropyl)-piperdin-4-yl]-6-bromoindoline | HCID 23377476 | 90% |
Reaction Steps
1-(Piperidin-4-yl)-6-bromoindoline (1.6 g) and 4-fluorophenoxypropyl bromide (1.6 g) were treated as in Example 2 to give the title compound (2.2 g) as a white powder (yield: 90%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07071201B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-d29c7b7a24244799ba89050c6599dab3 |
| Source note | uspto-grants-2006_07 |