HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,4-Difluorophenethyl bromide → 1-[1-(2,4-Difluorophenethyl)-piperidin-4-yl]-6-chloro-7-azaindoline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,4-Difluorophenethyl bromide | HCID 11298989 | — |
| Reactant | 1-(Piperidin-4-yl)-6-chloro-7-azaindoline | HCID 22038287 | — |
| Product | 1-[1-(2,4-Difluorophenethyl)-piperidin-4-yl]-6-chloro-7-azaindoline | HCID 22038121 | 7.8% |
Reaction Steps
1-(Piperidin-4-yl)-6-chloro-7-azaindoline (0.5 g) and 2,4-difluorophenethyl bromide (0.43 g) were treated as in Example 2 to give the hydrochloride (74 mg) of the title compound as a brown powder (yield: 7.8%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07071201B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-1d981b97ad054fe78432ba569c0c0283 |
| Source note | uspto-grants-2006_07 |