Sodium ion → 2-Chloro-6-(2,2-dimethyl-4-oxetan-3-ylpiperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine

HRID 179055Notes

Reaction equation

HRID 179055 reaction equation
[C:31]([O:32][BH-:33]([O:34][C:35](=[O:36])[CH3:37])[O:38][C:39](=[O:40])[CH3:41])(=[O:42])[CH3:43].[CH3:19][C:20]1([CH3:30])[CH2:21][N:22]([CH:26]2[CH2:27][O:28][CH2:29]2)[CH2:23][CH2:24][NH:25]1.[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH:11]=[O:12])[s:10]2.[Na+:44]>>[Cl:1][c:2]1[n:3][c:4]([N:13]2[CH2:14][CH2:15][O:16][CH2:17][CH2:18]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:25]1[C:20]([CH3:19])([CH3:30])[CH2:21][N:22]([CH:26]3[CH2:27][O:28][CH2:29]3)[CH2:23][CH2:24]1)[s:10]2

Participants

5

Reactant 4

HCID 923Sodium ionHCID 2724942TriacetoxyborohydrideHCID 457899852-Chloro-4-morpholinothieno[3,2-d]pyrimidine-6-carbaldehydeHCID 674922623,3-Dimethyl-1-(oxetan-3-yl)piperazine

Product 1

HCID 575067452-Chloro-6-(2,2-dimethyl-4-oxetan-3-ylpiperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine

Sources & evidence

ORD record
ord-fcb37ddbefbd45aaa929890907cedc32
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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