HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethanol → HCID 54429101, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethanol | HCID 702 | — |
| Reactant | 4-Methyloxybenzyl chloride | HCID 69993 | — |
| Reactant | (S)-2-Hydroxy-3-methylbutanoic acid | HCID 853180 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 54429101 | HCID 54429101 | — |
Reaction Steps
2-hydroxy-3-methyl-(S)-(+)-butyric acid (1.77 g) was esterified by alkylation with 4-methoxybenzyl chloride by the method described in Example A-I-1, step a. The title compound (3.10 g) was obtained after silica gel column chromatography (0, 1, 2% ethanol in dichloromethane). Rf (2% MeOH/CHCl3) 0.50.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07071173B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-cd103c8f4bed475198a3058a6dfc2bc0 |
| Source note | uspto-grants-2006_07 |