Ammonia → Ethyl 3-aminobutyrate

HRID 1790862Notes

Reaction equation

HRID 1790862 reaction equation
O[CH:2]([CH3:9])[CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5].[NH3:10]>>[NH2:10][CH:2]([CH3:9])[CH2:3][C:4]([O:6][CH2:7][CH3:8])=[O:5]

Participants

3

Reactant 2

HCID 222AmmoniaHCID 62572Ethyl 3-Hydroxybutyrate2×

Product 1

HCID 98103Ethyl 3-aminobutyrate

Procedure

The concentrations of the substrates prior to entering the reactor were 0.226 M for ethyl 3-hydroxy-n-butyrate and 1.630 M for aqueous ammonia. The reaction time was 0.201 second, and the aqueous solution obtained after the reaction was examined with a high performance liquid chromatography/mass spectroscopy apparatus, which confirmed that an amino group had been introduced into the ethyl 3-hydroxy-n-butyrate, and that ethyl 3-amino-n-butyrate had been produced. The ethyl 3-amino-n-butyrate concentration was 3.3 mM, and the reaction yield thereof was 1.5%.

Workup

  1. customthe aqueous solution obtained after the reaction

Sources & evidence

ORD record
ord-300070830e1d40019e62ab5969babd71
Source dataset
uspto-grants-2006_07
Patent number
US07071350B2

Reaction notes

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