HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 22042477, compound → HCID 22042441, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 22042477 | HCID 22042477 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Adams' catalyst | HCID 345198 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 22042441 | HCID 22042441 | — |
Reaction Steps
1.23 g of 153 is dissolved in THF, and 200 mg of platinum(IV) oxide is added in an argon stream. Using a hydrogenating apparatus, it is hydrogenated until no more hydrogen is consumed, flushed with nitrogen, filtered and concentrated by evaporation. The residue is chromatographed on silica gel with ethyl acetate/hexane, whereby 1.19 g of title compound 154 accumulates as a colorless oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07071344B1 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-94c948cc57194278aef42c5ab3b35ba8 |
| Source note | uspto-grants-2006_07 |