4-(2-Hydroxyethyl)indolin-2-one → HCID 69587015, compound

HRID 1790935Notes

Reaction equation

HRID 1790935 reaction equation
[OH:1][CH2:2][CH2:3][C:4]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:5]=1[CH2:6][C:7](=[O:13])[NH:8]2.[N:14]1([CH2:19][CH2:20][O:21][C:22]2[CH:23]=[C:24]3[C:28](=[CH:29][CH:30]=2)[NH:27][C:26]([CH:31]=O)=[CH:25]3)[CH2:18][CH2:17][CH2:16][CH2:15]1>>[OH:1][CH2:2][CH2:3][C:4]1[CH:12]=[CH:11][CH:10]=[C:9]2[C:5]=1[C:6](=[CH:31][C:26]1[NH:27][C:28]3[C:24]([CH:25]=1)=[CH:23][C:22]([O:21][CH2:20][CH2:19][N:14]1[CH2:18][CH2:17][CH2:16][CH2:15]1)=[CH:30][CH:29]=3)[C:7](=[O:13])[NH:8]2

Participants

3

Reactant 2

HCID 109430044-(2-Hydroxyethyl)indolin-2-oneHCID 220420925-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde

Product 1

HCID 69587015HCID 69587015, compound

Procedure

4-(2-Hydroxy-ethyl)-1,3-dihydro-indol-2-one was condensed with 5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.

Sources & evidence

ORD record
ord-21c464a4d863490dbf489ffc0acbc4dd
Source dataset
uspto-grants-2006_07
Patent number
US07071332B2

Reaction notes

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