5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde → HCID 69586954, compound

HRID 1790940Notes

Reaction equation

HRID 1790940 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8]2[CH:16]=[C:15]3[C:11]([CH2:12][C:13](=[O:17])[NH:14]3)=[CH:10][CH:9]=2)=[CH:4][CH:3]=1.[N:18]1([CH2:23][CH2:24][O:25][C:26]2[CH:27]=[C:28]3[C:32](=[CH:33][CH:34]=2)[NH:31][C:30]([CH:35]=O)=[CH:29]3)[CH2:22][CH2:21][CH2:20][CH2:19]1>>[F:1][C:2]1[CH:3]=[CH:4][C:5]([C:8]2[CH:16]=[C:15]3[C:11]([C:12](=[CH:35][C:30]4[NH:31][C:32]5[C:28]([CH:29]=4)=[CH:27][C:26]([O:25][CH2:24][CH2:23][N:18]4[CH2:22][CH2:21][CH2:20][CH2:19]4)=[CH:34][CH:33]=5)[C:13](=[O:17])[NH:14]3)=[CH:10][CH:9]=2)=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 220420925-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehydeHCID 220421726-(4-Fluorophenyl)-1,3-dihydro-2H-indol-2-one

Product 1

HCID 69586954HCID 69586954, compound

Procedure

6-(4-Fluoro-phenyl)-1,3-dihydro-indol-2-one was condensed with 5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.

Sources & evidence

ORD record
ord-1783069595d241b6a79d9f4b41a6ea47
Source dataset
uspto-grants-2006_07
Patent number
US07071332B2

Reaction notes

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