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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1790949Generated: October 30, 2026

5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde → 2-Oxo-3-[5-(2-pyrrolidin-1-yl-ethoxy)-1H-indol-2-ylmethylene]-2,3-dihydro-1H-indole-5-sulfonic acid (3-chloro-phenyl)-methyl-amide

https://huagongshe.com/reaction/1790949

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehydeHCID 22042092—
ReactantN-(3-chlorophenyl)-N-methyl-2-oxoindoline-5-sulfonamideHCID 44627952—
Product2-Oxo-3-[5-(2-pyrrolidin-1-yl-ethoxy)-1H-indol-2-ylmethylene]-2,3-dihydro-1H-indole-5-sulfonic acid (3-chloro-phenyl)-methyl-amideHCID 69898451—

Reaction Steps

2-Oxo-2,3-dihydro-1H-indole-5-sulfonic acid (3-chloro-phenyl)-methyl-amide was condensed with 5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07071332B2
Source datasetuspto-grants-2006_07
ORD IDord-5185e09d5e6d4195a51e1e81a27f719f
Source noteuspto-grants-2006_07