5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde → HCID 69344951, compound

HRID 1790952Notes

Reaction equation

HRID 1790952 reaction equation
[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][N:2]1[S:11]([C:14]1[CH:15]=[C:16]2[C:20](=[CH:21][CH:22]=1)[NH:19][C:18](=[O:23])[CH2:17]2)(=[O:13])=[O:12].[N:24]1([CH2:29][CH2:30][O:31][C:32]2[CH:33]=[C:34]3[C:38](=[CH:39][CH:40]=2)[NH:37][C:36]([CH:41]=O)=[CH:35]3)[CH2:28][CH2:27][CH2:26][CH2:25]1>>[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][N:2]1[S:11]([C:14]1[CH:15]=[C:16]2[C:20](=[CH:21][CH:22]=1)[NH:19][C:18](=[O:23])[C:17]2=[CH:41][C:36]1[NH:37][C:38]2[C:34]([CH:35]=1)=[CH:33][C:32]([O:31][CH2:30][CH2:29][N:24]1[CH2:28][CH2:27][CH2:26][CH2:25]1)=[CH:40][CH:39]=2)(=[O:13])=[O:12]

Participants

3

Reactant 2

HCID 220420925-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehydeHCID 22042103HCID 22042103, compound

Product 1

HCID 69344951HCID 69344951, compound

Procedure

5-(3,4-Dihydro-1H-isoquinoline-2-sulfonyl)-1,3-dihydro-indol-2-one was condensed with 5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.

Sources & evidence

ORD record
ord-1b57b2ba515740d182c9f72c3c926337
Source dataset
uspto-grants-2006_07
Patent number
US07071332B2

Reaction notes

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