5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde → HCID 69344151, compound

HRID 1790953Notes

Reaction equation

HRID 1790953 reaction equation
[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([S:11]([C:14]1[CH:15]=[C:16]3[C:20](=[CH:21][CH:22]=1)[NH:19][C:18](=[O:23])[CH2:17]3)(=[O:13])=[O:12])[CH2:6][CH2:5]2.[N:24]1([CH2:29][CH2:30][O:31][C:32]2[CH:33]=[C:34]3[C:38](=[CH:39][CH:40]=2)[NH:37][C:36]([CH:41]=O)=[CH:35]3)[CH2:28][CH2:27][CH2:26][CH2:25]1>>[Br:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]([S:11]([C:14]1[CH:15]=[C:16]3[C:20](=[CH:21][CH:22]=1)[NH:19][C:18](=[O:23])[C:17]3=[CH:41][C:36]1[NH:37][C:38]3[C:34]([CH:35]=1)=[CH:33][C:32]([O:31][CH2:30][CH2:29][N:24]1[CH2:28][CH2:27][CH2:26][CH2:25]1)=[CH:40][CH:39]=3)(=[O:12])=[O:13])[CH2:6][CH2:5]2

Participants

3

Reactant 2

HCID 220420925-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehydeHCID 22042164HCID 22042164, compound

Product 1

HCID 69344151HCID 69344151, compound

Procedure

5-(5-Bromo-2,3-dihydro-indole-1-sulfonyl)-1,3-dihydro-indol-2-one was condensed with 5-(2-pyrrolidin-1-yl-ethoxy)-1H-indole-2-carbaldehyde to give the title compound.

Sources & evidence

ORD record
ord-11d7d2d1664f48f6a210a9fc7908bcb9
Source dataset
uspto-grants-2006_07
Patent number
US07071332B2

Reaction notes

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