HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonium Hydroxide → 2-Oxoindoline-5-sulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonium Hydroxide | HCID 14923 | — |
| Reactant | 2-oxo-2,3-dihydro-1H-indole-5-sulfonyl chloride | HCID 4962506 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 2-Oxoindoline-5-sulfonamide | HCID 10198232 | 20% |
Reaction Steps
5-Chlorosulfonyl-2-oxindole (2.1 g) was added to 10 mL of ammonium hydroxide in 10 mL of ethanol and stirred at room temperature overnight. The mixture was concentrated and the solid collected by vacuum filtration to give 0.4 g (20% yield) of 5-aminosulfonyl-2-oxindole as an off-white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07071332B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-b820d9b2cbf24448ad491e3ac1473356 |
| Source note | uspto-grants-2006_07 |