2-Chlorophenothiazine → HCID 22027778, compound

Participants

Reaction Conditions

Reaction Steps

To a suspension of 2-chlorophenothiazine (2 g) in xylene (20 ml)was added diphosgene (3.4 g). The mixture was heated to 140° C. for 18 hrs. The mixture was then cooled and the xylene removed under reduced pressure. The residue was purified by flash chromatography (2–5% ethyl acetate/hexane) to afford the sub-title compound as a brown solid (2.04 g): 1H NMR (400 MHz, CDCl3) δ 7.26–7.43 (4H, m), 7.45–7.51 (1H, m), 7.59–7.68 (2H, m).

Provenance & Evidence