HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-2-methylindole → HCID 22030667, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-2-methylindole | HCID 2733992 | — |
| Reactant | 4-Chloro-6-methoxy-7-((1-methylpiperidin-4-yl)methoxy)quinazoline | HCID 11782230 | — |
| Product | HCID 22030667 | HCID 22030667 | 99.3% |
Reaction Steps
Using an analogous procedure to that described in Example 37, 4-chloro-6-methoxy-7-(1-methylpiperidin-4-ylmethoxy)quinazoline (50 mg, 0.155 mmol), (prepared as described for the starting material in Example 10), was reacted with 5-amino-2-methylindole (0.171 mmol) to give 6-methoxy-4-(2-methylindol-5-ylamino)-7-(1-methylpiperidin 4-ylmethoxy)quinazoline hydrochloride (72 mg, quant.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07074800B1 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-bda7ad14238d46d198d97acd5d1b374a |
| Source note | uspto-grants-2006_07 |