HCID 22033664, compound → HCID 22033669, compound

HRID 1791876Notes

Reaction equation

HRID 1791876 reaction equation
C[O:2][C:3](=[O:23])[C:4]1[CH:9]=[C:8]([O:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[NH2:17])[CH:7]=[CH:6][C:5]=1[NH:18][C:19](=[O:22])[CH2:20][CH3:21].CO[C:26](=O)[C:27]1C=C(SC2C=CC=CC=2N)C=C[C:28]=1NC(=O)CC>>[C:19]([NH:18][C:5]1[CH:6]=[CH:7][C:8]([O:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][C:12]=2[NH:17][CH2:26][CH2:27][CH3:28])=[CH:9][C:4]=1[C:3]([OH:2])=[O:23])(=[O:22])[CH2:20][CH3:21]

Participants

3

Reactant 2

HCID 22033664HCID 22033664, compoundHCID 69111274HCID 69111274, compound

Product 1

HCID 22033669HCID 22033669, compound

Procedure

The following compounds were obtained by reacting the intermediate 2-propionylamino-5-(2-amino-phenoxy)-benzoic methyl ester or 5-(2-amino-phenylsulfanyl)-2-propionylamino-benzoic acid methyl ester (EXAMPLE 17) with boronic acids according to EXAMPLE 6 or with aldehydes as described above.

Workup

  1. customThe following compounds were obtained

Sources & evidence

ORD record
ord-8f276a7881514110b2e1046b912dafe8
Source dataset
uspto-grants-2006_07
Patent number
US07074831B2

Reaction notes

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