Chlorosuccinimide → 1H-Purine-2,6-dione, 3,7-dihydro-8-chloro-7-(2-chlorophenyl)-1,3-dimethyl-

Participants

Reaction Steps

7-(2-Chlorophenyl)-1,3-dimethyl-3,7-dihydropurine-2,6-dione (138 mg) and N-chlorosuccinimide (78 mg) were suspended in N,N-dimethylformamide (1 ml). The reaction mixture was stirred at room temperature for 2 hours, diluted with ethyl acetate, and washed with water. The organic layer was dried over anhydrous magnesium sulfate, filtered, and the filtrate was concentrated under reduced pressure to give 151 mg of the title compound.

Provenance & Evidence