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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1792041Generated: November 3, 2026

HCID 23536934, compound → HCID 23081909, compound

https://huagongshe.com/reaction/1792041

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 23536934HCID 23536934—
CatalystPalladiumHCID 23938—
SolventAcetic AcidHCID 176—
ProductHCID 23081909HCID 23081909101.3%

Reaction Steps

4-[7-Benzyl-1-(2,2-dimethylpropionyloxymethyl)-3-methyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl]piperazine-1-carboxylic acid tert-butyl ester (2.227 g) was dissolved in acetic acid (100 ml), and 10% palladium on carbon (1 g) was added thereto. The reaction mixture was stirred under hydrogen atmosphere at room temperature overnight, filtered, and the filtrate was concentrated to give 1.89 g of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07074798B2
Source datasetuspto-grants-2006_07
ORD IDord-8edc079a9cfc4fa4baaa2531b276fd8e
Source noteuspto-grants-2006_07