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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1792047Generated: November 4, 2026

Ethyl Acetate → HCID 23536933, compound

https://huagongshe.com/reaction/1792047

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetateHCID 8857—
ReactantPotassium CarbonateHCID 11430—
ReactantMethyl bromoacetateHCID 60984—
ReactantHCID 23536936HCID 23536936—
SolventDimethylformamideHCID 6228—
ProductHCID 23536933HCID 23536933—

Reaction Steps

4-[7-(2-Chlorophenyl)-1-(2,2-dimethylpropionyloxymethyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl]piperazine-1-carboxylic acid tert-butyl ester (107 mg) was dissolved in N,N-dimethylformamide (2 ml), and methyl bromoacetate (0.025 ml) and potassium carbonate (50 mg) were added to the solution. Then, the mixture was stirred at room temperature overnight. Ethyl acetate was added to the reaction mixture, and the mixture was washed with water. The organic layer was concentrated to give 139 mg of the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07074798B2
Source datasetuspto-grants-2006_07
ORD IDord-0fc3c0473620495092f8d450da25bdf6
Source noteuspto-grants-2006_07