HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 23536933, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | Methyl bromoacetate | HCID 60984 | — |
| Reactant | HCID 23536936 | HCID 23536936 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 23536933 | HCID 23536933 | — |
Reaction Steps
4-[7-(2-Chlorophenyl)-1-(2,2-dimethylpropionyloxymethyl)-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl]piperazine-1-carboxylic acid tert-butyl ester (107 mg) was dissolved in N,N-dimethylformamide (2 ml), and methyl bromoacetate (0.025 ml) and potassium carbonate (50 mg) were added to the solution. Then, the mixture was stirred at room temperature overnight. Ethyl acetate was added to the reaction mixture, and the mixture was washed with water. The organic layer was concentrated to give 139 mg of the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07074798B2 |
| Source dataset | uspto-grants-2006_07 |
| ORD ID | ord-0fc3c0473620495092f8d450da25bdf6 |
| Source note | uspto-grants-2006_07 |