Trifluoroacetic acid → [1-Methyl-2,6-dioxo-8-(piperazin-1-yl)-7-(2-vinylphenyl)-1,2,6,7-tetrahydropurin-3-yl]acetic acid ethyl ester trifluoroacetate

Participants

Reaction Steps

4-[3-Ethoxycarbonylmethyl-1-methyl-2,6-dioxo-7-(2-vinylphenyl)-2,3,6,7-tetrahydro-1H-purin-8-yl]piperazine-1-carboxylic acid tert-butyl ester (8 mg) was dissolved in trifluoroacetic acid and the solution was concentrated. The residue was purified by reversed phase high performance liquid chromatography to give 2.68 mg of the title compound.

Provenance & Evidence