Dichloromethane → 4-[6-(5-Methanesulfonyl-2,3-dihydro-indol-1-yl)-pyrimidin-4-yloxy]-piperidine-1-carboxylic acid 1-(2-fluoro-benzyl)-pyrrolidin-3-yl ester
Reaction equation
[Cl:44][CH2:45][Cl:46].[F:1][c:2]1[c:3]([CH:4]=[O:5])[cH:6][cH:7][cH:8][cH:9]1.[NH:10]1[CH2:11][CH:12]([O:15][C:16](=[O:17])[N:18]2[CH2:19][CH2:20][CH:21]([O:24][c:25]3[n:26][cH:27][n:28][c:29]([N:31]4[CH2:32][CH2:33][c:34]5[cH:35][c:36]([S:40](=[O:41])(=[O:42])[CH3:43])[cH:37][cH:38][c:39]54)[cH:30]3)[CH2:22][CH2:23]2)[CH2:13][CH2:14]1>>[F:1][c:2]1[c:3]([CH2:4][N:10]2[CH2:11][CH:12]([O:15][C:16](=[O:17])[N:18]3[CH2:19][CH2:20][CH:21]([O:24][c:25]4[n:26][cH:27][n:28][c:29]([N:31]5[CH2:32][CH2:33][c:34]6[cH:35][c:36]([S:40](=[O:41])(=[O:42])[CH3:43])[cH:37][cH:38][c:39]65)[cH:30]4)[CH2:22][CH2:23]3)[CH2:13][CH2:14]2)[cH:6][cH:7][cH:8][cH:9]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-79f7e04c8ec241c4bb6507f1841ea8a0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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