HRID1792392

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：COc1ccc(C2(C)CSc3cc(OC)ccc3C2CCCCCCCCCSCCCCC#N)cc1

HCID22033061

未命名化合物

结构：CC1(c2ccc(O)cc2)CSc2cc(O)ccc2C1CCCCCCCCCSCCCC(F)(F)C(F)(F)F

HCID22033340

未命名化合物

PRODUCTS

生成物

结构：CC1(c2ccc(O)cc2)CSc2cc(O)ccc2C1CCCCCCCCCSCCCCC#N

HCID22033367

未命名化合物

PROCEDURE

实验过程

The title compound was prepared from 4-[9-(4-cyanobutylthio)nonyl]-7-methoxy-3-(4-methoxyphenyl)-3-methylthiochroman according to the same method for the synthesis of (3RS,4RS)-7-hydroxy-3-(4-hydroxyphenyl)-3-methyl-4-[9-(4,4,5,5,5-pentafluoropentylthio)nonyl]thiochroman described in International Patent Appln. No. PCT/KR97/00265.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-ed6dc82dc74744d98d88e5069ca0df98
来源数据集: uspto-grants-2006_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07074819B2
来源说明: uspto-grants-2006_07

反应 SMILES

[C:1]([CH2:3][CH2:4][CH2:5][CH2:6][S:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH:17]1[C:26]2[C:21](=[CH:22][C:23]([O:27]C)=[CH:24][CH:25]=2)[S:20][CH2:19][C:18]1([C:30]1[CH:35]=[CH:34][C:33]([O:36]C)=[CH:32][CH:31]=1)[CH3:29])#[N:2].OC1C=C2C(C(CCCCCCCCCSCCCC(F)(F)C(F)(F)F)C(C3C=CC(O)=CC=3)(C)CS2)=CC=1>>[C:1]([CH2:3][CH2:4][CH2:5][CH2:6][S:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH:17]1[C:26]2[C:21](=[CH:22][C:23]([OH:27])=[CH:24][CH:25]=2)[S:20][CH2:19][C:18]1([C:30]1[CH:35]=[CH:34][C:33]([OH:36])=[CH:32][CH:31]=1)[CH3:29])#[N:2]