4-[9-(t-Butyldimethylsilyloxy)nonyl]-7-methoxymethoxy-3-(4-methoxymethoxyphenyl)-3-methylchroman → 4-[9-(t-Butyldimethylsilyloxy)nonyl]-3-(4-hydoxyphenyl)-7-methoxymethyloxy-3-methylchroman
Reaction equation
[Si](OCCCCCCCC#CC1C2C(=CC(OCOC)=CC=2)OCC1C)(C(C)(C)C)(C)C.[Si:33]([O:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH:50]1[C:59]2[C:54](=[CH:55][C:56]([O:60][CH2:61][O:62][CH3:63])=[CH:57][CH:58]=2)[O:53][CH2:52][C:51]1([C:65]1[CH:70]=[CH:69][C:68]([O:71]COC)=[CH:67][CH:66]=1)[CH3:64])([C:36]([CH3:39])([CH3:38])[CH3:37])([CH3:35])[CH3:34]>>[Si:33]([O:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH:50]1[C:59]2[C:54](=[CH:55][C:56]([O:60][CH2:61][O:62][CH3:63])=[CH:57][CH:58]=2)[O:53][CH2:52][C:51]1([C:65]1[CH:66]=[CH:67][C:68]([OH:71])=[CH:69][CH:70]=1)[CH3:64])([C:36]([CH3:39])([CH3:37])[CH3:38])([CH3:35])[CH3:34]Participants
3
Reactant 2
Product 1
Procedure
The title compound was prepared from 3-(4-benzyloxy]phenyl)-4-[9-(t-butyldimethylsilyloxy)-1-nonynyl]-7-methoxymethyloxy-3-methylchroman according to the same method for the synthesis of 4-[9-(t-butyldimethylsilyloxy)-1-nonyl]-7-methoxymethyloxy-3-(4-methoxymethyloxyphenyl)-3-methylchroman described in International Patent Appln. No. PCT/KR97/00265.
Sources & evidence
- ORD record
- ord-28aa8e3571ed4446a2010d33b45c1a23
- Source dataset
- uspto-grants-2006_07
- Patent number
- US07074819B2
Reaction notes
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