7-Methoxymethoxy-3-(4-methoxymethoxyphenyl)-3-methylchroman-4-one → 4-{3-[4-(3-t-Butyldimethylsilyloxypropyl)phenoxy]-1-propynyl}-7-methoxymethyloxy-3-(4-methoxymethyloxyphenyl)-3-methylchroman-4-ol

Participants

Role	Name	HCID	Charge
Reactant	7-Methoxymethoxy-3-(4-methoxymethoxyphenyl)-3-methylchroman-4-one	HCID 15481763	—
Reactant	4-[9-(t-Butyldimethylsilyloxy)1-nonynyl]-7-methoxy-3-(4-methoxyphenyl)-3-methylthiochroman	HCID 22033428	—
Reactant	3-[4-(3-t-Butyldimethylsilyloxypropyl)phenoxy]-1-propyn	HCID 54014130	—
Product	4-{3-[4-(3-t-Butyldimethylsilyloxypropyl)phenoxy]-1-propynyl}-7-methoxymethyloxy-3-(4-methoxymethyloxyphenyl)-3-methylchroman-4-ol	HCID 22033320	—

Reaction Steps

The title compound was prepared from 7-methoxymethyloxy-3-(4-methoxymethyloxyphenyl)-3-methylchroman-4-one and 3-[4-(3-t-butyldimethylsilyloxypropyl)phenoxy]-1-propyn according to the same method for the synthesis of 4-[9-(t-butyldimethylsilyloxy)1-nonynyl]-7-methoxy-3-(4-methoxyphenyl)-3-methylthiochroman.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07074819B2
Source dataset	uspto-grants-2006_07
ORD ID	ord-4fa541ffae70467b9e3a401e83db8b40
Source note	uspto-grants-2006_07