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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1792399Generated: November 3, 2026

4-(9-Hydroxynonyl)-7-methoxymethoxy-3-(4-methoxymethoxyphenyl)-3-methylchroman → 4-{3-[4-(3-Hydroxypropyl)phenoxy]-1-propyl}-7-methoxymethyloxy-3-(4-methoxymethyloxyphenyl)-3-methylchroman

https://huagongshe.com/reaction/1792399

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(9-Hydroxynonyl)-7-methoxymethoxy-3-(4-methoxymethoxyphenyl)-3-methylchromanHCID 15481759—
Reactant(3RS,4RS)-4-{3-[4-(3-t-butyl-dimethylsilyloxypropyl)phenoxy]-1-propyl}-7-methoxymethyloxy-3-(4-methoxymethyloxyphenyl)-3-methylchromanHCID 22033132—
Product4-{3-[4-(3-Hydroxypropyl)phenoxy]-1-propyl}-7-methoxymethyloxy-3-(4-methoxymethyloxyphenyl)-3-methylchromanHCID 22033052—

Reaction Steps

The title compound was prepared from (3RS,4RS)-4-{3-[4-(3-t-butyl-dimethylsilyloxypropyl)phenoxy]-1-propyl}-7-methoxymethyloxy-3-(4-methoxymethyloxyphenyl)-3-methylchroman according to the same method for the synthesis of 4-[9-hydroxy-1-nonyl]-7-methoxymethyloxy-3-(4-methoxymethyloxyphenyl)-3-methylchroman described in International Patent Appln. No. PCT/KR97/00265.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07074819B2
Source datasetuspto-grants-2006_07
ORD IDord-6c73446eef51478ba3bef8d5670c76fa
Source noteuspto-grants-2006_07