Dimethyl Sulfoxide → 4-(4-Amino-3-fluorophenoxy)pyridine-2-carboxamide
Reaction equation
[CH3:10][C:11]([CH3:12])([O-:13])[CH3:14].[CH3:28][S:29](=[O:30])[CH3:31].[Cl:16][c:17]1[cH:18][c:19]([C:23](=[O:24])[NH2:25])[n:20][cH:21][cH:22]1.[K+:15].[NH2:1][c:2]1[c:3]([F:9])[cH:4][c:5]([OH:8])[cH:6][cH:7]1.[Na+:27].[OH-:26]>>[NH2:1][c:2]1[c:3]([F:9])[cH:4][c:5]([O:8][c:17]2[cH:18][c:19]([C:23](=[O:24])[NH2:25])[n:20][cH:21][cH:22]2)[cH:6][cH:7]1Participants
8
Sources & evidence
- ORD record
- ord-defd8b7e01b24fb8aa869dbd1c57f95c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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