2-(Tributylstannyl)pyridine → HCID 22030975, compound

HRID 1792518Notes

Reaction equation

Br[C:2]1[S:6][C:5]([C:7]2[N:11]3[CH:12]=[C:13]([C:16]4[C:17]([C:40]5[CH:45]=[CH:44][C:43]([F:46])=[CH:42][CH:41]=5)=[N:18][N:19]([C:21]([C:34]5[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=5)([C:28]5[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=5)[C:22]5[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=5)[CH:20]=4)[CH:14]=[CH:15][C:10]3=[N:9][CH:8]=2)=[CH:4][CH:3]=1.C([Sn](CCCC)(CCCC)[C:52]1[CH:57]=[CH:56][CH:55]=[CH:54][N:53]=1)CCC>>[F:46][C:43]1[CH:44]=[CH:45][C:40]([C:17]2[C:16]([C:13]3[CH:14]=[CH:15][C:10]4[N:11]([C:7]([C:5]5[S:6][C:2]([C:52]6[CH:57]=[CH:56][CH:55]=[CH:54][N:53]=6)=[CH:3][CH:4]=5)=[CH:8][N:9]=4)[CH:12]=3)=[CH:20][N:19]([C:21]([C:34]3[CH:39]=[CH:38][CH:37]=[CH:36][CH:35]=3)([C:28]3[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=3)[C:22]3[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=3)[N:18]=2)=[CH:41][CH:42]=1

Participants

Reactant 2

HCID 6077842-(Tributylstannyl)pyridine

HCID 22031970HCID 22031970, compound

Product 1

HCID 22030975HCID 22030975, compound

Procedure

150 mg of 3-(5-bromo-2-thienyl)-6-[3-(4-fluorophenyl)-1-trityl-1H-4-pyrazolyl]imidazo[1,2-a]pyridine obtained in Example 4 and 0.13 mL of 2-(tri-n-butylstannyl)pyridine were reacted in the same manner as in Example 21, to give 137 mg of the title compound as a yellow amorphous.

Sources & evidence

ORD record: ord-ce600d8bef3f43d48a6b925f547a42ac
Source dataset: uspto-grants-2006_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07074801B1

Reaction notes

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